Guy Hanke

“I know of nothing sublime that is not some modification of power”   Edmund Burke

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  • Tournaire MD, Scharff LB, Kramer M, Goss T, Vuorijoki L, Rodriguez-Heredia M, Wilson S, Kruse I, Ruban AV, Balk JL, Hase T, Jensen PE, Hanke GT (2021) Ferredoxin C2 is required for chlorophyll biosynthesis and accumulation of photosynthetic antennae in Arabidopsis  Plant and Cell Physiol. DOI: 10.1111/pce.14667.


  • Rodriguez-Heredia M, Saccon F, Wilson S, Finazzi G, Ruban AV, Hanke GT (2021) Protection of photosystem I during sudden light stress depends on ferredoxin:NADP(H) reductase abundance and interactions. Plant Physiol. 188: 1028–1042.


  • Richardson KH, Wright JJ, Šimėnas M, Thiemann J, Esteves AM, McGuire G, Myers WK, Morton JJL, Hippler M, Nowaczyk MM, Hanke GT (joint corresponding), Roessler MM (2021) Functional basis of electron transport within photosynthetic complex 1. Nat Commun 12:5387. DOI: 10.1038/s41467-021-25527-1

  • Sarewicz M, Pintscher S, Pietras R, Borek A, Bujnowicz Ł, Hanke G, Cramer WA, Finazzi G, Osyczka A (2021) Catalytic Reactions and Energy Conservation in the Cytochrome bc1 and b6f Complexes of Energy-Transducing Membranes. Chem Rev. 121:2020-2108. DOI: 10.1021/acs.chemrev.0c00712

  • Kramer M, Rodriguez-Heredia M, Saccon F, Mosebach L, Twachtmann M, Krieger-Liszkay A, Duffy C, Knell RJ, Finazzi G, Hanke GT (2021) Regulation of photosynthetic electron flow on dark to light transition by ferredoxin:NADP(H) oxidoreductase interactions. Elife. 10:e56088. DOI: 10.7554/eLife.56088.

  • Shimakawa G, Hanawa H, Wada S, Hanke GT, Matsuda Y, Miyake C. (2021) Front Plant Sci. 12:668805. DOI: 10.3389/fpls.2021.668805

  • Lea-Smith DJ, Hanke GT (2021). Electron transport in cyanobacteria and its potential in bioproduction. Chapter in Cyanobacteria Biotechnology (Wiley-VCH GmbH). 33-63.

Since 2015

  • Mellor SB, Vinde MH, Nielsen AZ, Hanke GT, Abdiaziz K, Roessler MM, Burow M, Motawia MS, Møller BL, Jensen PE. (2019) Defining optimal electron transfer partners for light-driven cytochrome P450 reactions. Metab Eng. 55:33-43

  • Herbst J, Girke A, Hajirezaei MR, Hanke G and Grimm B (2018) Potential roles of YCF54 and ferredoxin‐NADPH reductase for magnesium protoporphyrin monomethylester cyclase. Plant J. 94(3):485-496

  • Schorsch M, Kramer M, Goss T, Eisenhut M, Robinson N, Osman D, Wilde A, Sadaf S, Brückler H, Walder L, Scheibe R, Hase T, Hanke GT. (2018) A unique ferredoxin acts as a player in the low-iron response of photosynthetic organisms. Proc Natl Acad Sci U S A.  115(51):E12111-E12120. doi: 10.1073/pnas.1810379115.

  • Hanke GT and Scheibe RS (2018) The contribution of electron transfer after photosystem I to balancing photosynthesis. Photosynthesis and Bioenergetics Eds. Barber J and Ruban A. 277-304

  • Hanke GT (2017) preface: Ferredoxin. Guest Editors introduction to the special issue. Photosynth Res 134:233–234

  • Shinohara M, Kurisu G, Hanke G, Bowsher C, Hase T, Kimata Ariga, Y. (2017) Structural basis for the isotype-specific interactions of ferredoxin and ferredoxin: NADP+ oxidoreductase: an evolutionary switch between photosynthetic and heterotrophic assimilation. Photosyn Res 134(3):281-289

  • Mosebach L, Heilmann C, Mutoh R, Gäbelein P, Steinbeck J, Happe T, Ikegami T, Hanke G, Kurisu G, Hippler M (2017) Association of Ferredoxin:NADP+ oxidoreductase with the photosynthetic apparatus modulates electron transfer in Chlamydomonas reinhardtii. Photosynth Res. 134(3):291-306

  • Kozuleva M, Goss T, Twachtmann M, Rudi K, Trapka J, Selinski J, Ivanov B, Garapathi P, Steinhoff HJ, Hase T, Scheibe R, Klare JP, Hanke G (2016) Ferredoxin:NADP(H) oxidoreductase abundance and location influences redox poise and stress tolerance. Plant Physiol. 172:1480-1493

  • Hachiya T, Ueda N, Kitagawa M, Hanke G, Suzuki A, Hase T, Sakakibara H (2016) Arabidopsis Root-Type Ferredoxin:NADP(H) Oxidoreductase 2 Is Involved in Detoxification of Nitrite in Roots. Plant Cell Physiol. 57:2440-2450

  • Kim JY, Kinoshita M, Kume S, Hanke GT, Sugiki T, Ladbury JE, Kojima C, Ikegami T, Kurisu G, Goto Y, Hase T, Lee YH (2016) Noncovalent forces tune the electron transfer complex between ferredoxin and sulfite reductase to optimize enzymatic activity. Biochem J. 473(21):3837-3854


  • Lehtimäki N, Koskela MM, Dahlström KM, Pakula E, Lintala M, Scholz M, Hippler M, Hanke GT, Rokka A, Battchikova N,Salminen TA, Mulo P (2014) Post-translational modifications of ferredoxin-NADP+ oxidoreductase in Arabidopsis thaliana chloroplasts. Plant Physiol 166, 1764-76

  • Goss T, Hanke GT (2014) The end of the line: can ferredoxin and ferredoxin NADP(H) oxidoreductase determine the fate of photosynthetic electrons? Curr Protein Pept Sci 15, 385-393

  • Selinski J, König N, Wellmeyer B, Hanke GT, Linke V, Neuhaus HE, Scheibe R (2014) The plastid-localized NAD-dependent malate dehydrogenase is crucial for energy homeostasis in developing Arabidopsis thaliana seeds. Mol Plant 7, 170-186

  • Blanco NE, Ceccoli RD, Dalla Vía MV, Voss I, Segretin ME, Bravo-Almonacid FF, Melzer M, Hajirezaei M, Scheibe R, Hanke GT (2013) Expression of the minor isoform pea ferredoxin in tobacco alters photosynthetic electron partitioning and enhances cyclic electron flow. Plant Phys 161, 866-879

  • Busch KB, Deckers-Hebestreit G, Hanke GT, Mulkidjanian AY (2013) Dynamics of bioenergetic membranes. Biol Chem 394, 163-188

  • Zachgo S, Hanke GT, Scheibe R (2013) Plant Cell Microcompartments, a signaling perspective. Biol Chem 394, 203-216

  • Hanke GT, Mulo P (2013) Plant type ferredoxins and ferredoxin-dependent metabolism. Plant Cell Environ. 36, 1071-1084

  • Twachtmann M, Altmann B, Muraki N, Okutani S, Voss I, Kurisu G, Hase T, Hanke GT (2012) N-terminal structure of ferredoxin:NADP+ reductase determines recruitment into different thylakoid membrane complexes. Plant Cell 24, 2979-2991

  • Ceccoli RD, Blanco NE, Segertin ME, Hanke GT, Scheibe RS, Hajirezaei MR, Bravo-Almonacid FF, Carrillo N (2012) Flavodoxin displays dose-dependent effects on photosynthesis and stress tolerance when expressed in transgenic tobacco plants. Planta 236, 1447-1458

  • Voss I, Goss T, Murozuka E, Altmann B, McLean KJ, Rigby SEJ, Munro A, Scheibe R, Hase T, Hanke GT (2011) FdC1, a novel ferredoxin protein capable of alternative electron partitioning, increases in conditions of acceptor limitation at PSI. J Biol Chem 286, 50-59

  • Bowsher CG, Eyres LM, Gummadova JO, Hothi P, McLean KJ, Munro AW, Scrutton NS, Hanke GT, Sakakibara Y, Hase T (2011) Identification of N-terminal regions of wheat leaf ferredoxin NADP+ oxidoreductase important for interaction with ferredoxin. Biochemistry-US 50, 1778-1787

  • Hanke GT, Satomi Y, Shinmura K, Takao T, Hase T (2011) A screen for potential ferredoxin electron transfer partners uncovers new, redox dependent interactions. BBA-Proteins Proteom 1814, 366-374

  • Hanke GT, Holtgrefe S, König N, Strodkötter I, Voss I, and Scheibe R (2009) Use of transgenic plants to uncover strategies for maintenance of  homeostasis during photosynthesis. Adv Bot Res 52, 209-251

  • Hanke GT, and Hase T. (2008) Variable photosynthetic roles of two leaf-type ferredoxins in Arabidopsis, as revealed by RNA interference. Photochem Photobiol 84, 1302-1309

  • Hanke GT, Endo T, Sato F, Hase T (2008) Altered photosynthetic electron channeling into cyclic electron flow and nitrite assimilation in a mutant of ferredoxin:NADP(H) reductase. Plant Cell Environ 31, 1017-1028

  • Gummadova JO, Fletcher GJ, Moolna A, Hanke GT, Hase T, Bowsher CG (2007) Expression of multiple forms of ferredoxin NADP+ oxidoreductase in wheat leaves. J Ex Bot. 58, 3971-3985

  • Bowsher CG, Lacey AE, Hanke GT, Clarkson DT, Saker LR, Stulen I, Emes MJ (2007) The effect of Glc6P uptake and its subsequent oxidation within pea root plastids on nitrite reduction and glutamate synthesis. J Ex Bot 58, 1109 – 1118

  • Gou P, Hanke GT, Kimata-Ariga Y, Standley D, Kubo A, Taniguchi I, Nakamura H, Hase T (2006) Higher order structure contributes to specific differences in redox potential and electron transfer efficiency of root and leaf ferredoxins. Biochem

  •  45, 14389-14396

  • Okutani S, Hanke GT, Satomi T, Takao T, Kurisu G, Suzuki A, Hase T (2005) Three maize leaf ferredoxin:NADP(H) oxidoreductases vary in sub-chloroplast location, expression, and interaction with ferredoxin. Plant Physiol 139, 1451-1459

  • Hanke GT, Okutani S, Satomi Y, Takao T, Suzuki A, Hase T (2005) Multiple isoproteins of FNR in Arabidopsis: evidence for different contributions to chloroplast function and nitrogen assimilation. Plant Cell Environ 28. 1146-1157

  • Kurisu G, Nishiyama D, Kusunoki M, Fujikawa S, Katoh M, Hanke GT, Hase T, Teshima K (2005) A structural basis of Equisetum arvense Ferredoxin Isoform II producing an alternative electron transfer with ferredoxin-NADP+ reductase. J Biol Chem 280, 2275-2281

  • Hanke GT, Kurisu G, Kusunoki M, Hase T (2004) Fd : FNR electron transfer complexes: evolutionary refinement of structural interactions. Photosynth Res 81, 317-327

  • Hanke GT, Kimata-Ariga Y, Taniguchi I, Hase T (2004) A post genomic characterization of Arabidopsis ferredoxins. Plant Physiol. 134, 255-264

  • Nakayama M, Hanke GT, Hase T (2003) Ferredoxin-mediating regulation of redox metabolisms in plastids. Protein, Nucleic acid and Enzyme. 48, 2138-2144 (Japanese)

  • Hanke GT, Northrop FD, Devine GR, Bothwell JH, Davis JM (2001) Chloride channel antagonists perturb growth and morphology of Neurospora crassa. FEMS Microbiol Lett 201, 243-247

  • Hanke GT, Bowsher CG, Jones M, Tetlow I, Emes MJ (1999) Proteoliposomes and plant transport proteins. J Exp Bot 50, 1715-1726